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The bidomain model is a mathematical model to define the electrical activity of the heart. It consists in a continuum (volume-average) approach in which the cardiac mictrostructure is defined in terms of muscle fibers grouped in sheets, creating a complex three-dimensional structure with anisotropical properties. Then, to define the electrical activity, two interpenetrating domains are considered, which are the intracellular and extracellular domains, representing respectively the space inside the cells and the region between them. Three examples of the impact of unequal anisotropy ratios are

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