In developmental biology, bioelectricity refers to the regulation of cell, tissue, and organ-level patterning and behavior as the result of endogenous electrically mediated signaling. Cells and tissues of all types use ion fluxes to communicate electrically. The charge carrier in bioelectricity is the ion (charged atom), and an electric current and field is generated whenever a net ion flux occurs. Endogenous electric currents and fields, ion fluxes, and differences in resting potential across tissues comprise an ancient and highly conserved communicating and signaling system. It functions alongside (in series and in parallel to) biochemical factors, transcriptional networks, and other physical forces to regulate the cell behavior and large-scale patterning during embryogenesis, regenerati