Edward McClain (March 7, 1899 – August 24, 1985), nicknamed "Boots", was an American Negro league infielder in the 1920s. A native of Louisville, Kentucky, McClain made his Negro leagues debut in 1920 with the Dayton Marcos and Indianapolis ABCs. He went on to play for several teams, finishing his career back in Dayton in 1926. McClain died in Columbus, Ohio in 1985 at age 86.