Brad Keywell (born October 1969) is an American entrepreneur from Michigan. He is the founder and executive chairman of Uptake Technologies, an industrial AI software provider. He is an early investor of Tempus Labs, co-founder of Groupon, Echo Global Logistics, Mediaocean, DRIVIN, and Lightbank. As of August 2020, his net worth was estimated at US$ 2.7 billion. Keywell is the recipient of the 2019 Ernst & Young World Entrepreneur Of The Year award.