The Capt. Charles C. Henderson House is a historic house at Henderson and 10th Streets in Arkadelphia, Arkansas. Built in 1906 and significantly altered in 1918–20, it is the largest and most elaborate house of that period on 10th Street. When first built, it was a 2+1⁄2-story hip-roofed Queen Anne style house with some Classical Revival elements. Its most prominent feature from this period is the turret with elaborate finial. In 1918-20 Henderson significantly modified the house, added the boxy two-story Craftsman-style porch. The house is now on the campus of Henderson State University.