Cayetana blanca, also known as Cayetana or Jaén, is a white Spanish wine grape. It is grown mainly in the south of Spain, especially in Extremadura and in the Jerez region where it is distilled for use in brandy production. It is mentioned in the 1513 treatise Obra de Agricultura by Gabriel Alonso de Herrera. It may have originated in the Alentejo region of Portugal, although it is now rare in that area. Cayetana Blanca was the third most planted white grape variety in Spain, with 39,919 ha (98,640 acres) in 2015, totalling 4% of the grapes and 9% of the white variety hectarage.