Charles IV of Alençon (2 September 1489 in Alençon – 11 April 1525 in Lyon) was the son of René of Alençon and Margaret of Vaudémont. He succeeded his father in 1492 as Duke of Alençon and Count of Perche, and was also Count of Armagnac, Fézensac, Viscount of Rodez, Count of Fezensaguet, l'Isle-Jourdain, and Perdiac. In 1509 he married Margaret of Angoulême, sister to Francis, Duke of Valois, who would in 1515 become King Francis I of France. Their marriage was childless: his wife was allowed to retain most of his titles.