Charlotte (28 June 1444 – 16 July 1487) was the Queen of Cyprus from 1458 until 1464. She was the eldest and only surviving daughter of King John II of Cyprus and Helena Palaiologina. At the age of 14, she succeeded to the Cypriot throne upon the death of her father. Her illegitimate half-brother, James, challenged her right to the crown. With the support of the Egyptians, he forced her to flee the island in 1463, and he was later crowned king. She made a military attempt to regain her throne, but was unsuccessful, and died childless in Rome.