Cobbs Creek is a neighborhood located in the West Philadelphia section of Philadelphia, Pennsylvania, United States, named for the creek which forms part of Philadelphia's western border. Cobbs Creek is generally bounded by Market Street to the north, Baltimore Avenue to the south, 52nd Street to the east, and the border of Upper Darby along Cobbs Creek to the West. Also listed on the National Register of Historic Places are the Holmes Junior High School and Walnut Park Plaza Hotel.