The enzyme cocaine esterase (EC 3.1.1.84, CocE, hCE2, hCE-2, human carboxylesterase 2; systematic name cocaine benzoylhydrolase) catalyses the reaction cocaine + H2O ecgonine methyl ester + benzoate Rhodococcus sp. strain MB1 and Pseudomonas maltophilia strain MB11L can utilize cocaine as sole source of carbon and energy. The theoretical molecular mass is 62,128 Da. This enzyme and redesigned versions of it have been studied as a potential treatment for cocaine addiction in humans.