Courtois Creek (locally /ˈkoʊtəweɪ/) is a 38.6-mile-long (62.1 km) stream in southern Missouri, United States. It shares its name with the nearby town of Courtois and is in the Courtois Hills region of the Missouri Ozarks. According to the information in the Ramsay Place Names File at the University of Missouri, the creek was "doubtless named for some French settler, but his identity has not been ascertained".