Damián Macaluso Rojas (born March 9, 1980 in Montevideo) is a Uruguayan footballer of Spanish and Italian descent. He plays as a defender for Montevideo Wanderers. Before joining AS Nancy in summer 2006, he also played for Racing Club de Montevideo, Club Atlético River Plate (Uruguay). He played in Guatemala for Cobán Imperial and helped them win the 2004 Clausura tournament. In June 2012 he signed with Peñarol.