Diego de Leyva (c. 1580–1637) was a Spanish painter. He was born at Haro in La Rioja. He is supposed to have spent his youth at Rome, and returned to Spain a painter, and settled at Burgos. In 1628 he was commissioned by the Chapter of Burgos to paint the portraits of certain dignitaries for the chapel of St. Catalina in the cathedral, and for the chapel of the Virgin he painted a picture of the Presentation.