Doctor De Soto is a picture book for children written and illustrated by William Steig and first published in 1982. It features a mouse dentist who must help a fox with a toothache without being eaten. Steig and his book won the 1983 National Book Award for Children's Books in category Picture Books, Hardcover, as did Barbara Cooney for Miss Rumphius. Doctor De Soto was also recognized as a Newbery Honor Book. At 32 pages it is one of the shortest to be honored in that awards program.