Down to the Bone is a 2004 American independent drama film, directed by Debra Granik and written by Granik and Richard Lieske. It stars Vera Farmiga, who received a Best Actress Award from the Los Angeles Film Critics Association for her role as the drug addicted Irene. The film premiered at the Sundance Film Festival on January 15, 2004, where it won the Director's Award (Granik) and the Special Jury Prize for Acting (Farmiga). The film received a limited release in the United States on November 25, 2005.