The Duke of York, known as the Duke of York Hotel for many years and now as Duke Live, is a historic structure in Leslieville, Toronto, Ontario. It is located at 1225 Queen Street East, at the corner of Queen Street and Leslie Avenue. The building site was originally known as "Uncle Tom's Cabin", presumably after the novel or Ontario site of the same name. A brick structure on the same lot, originally known as the Morin House, was constructed in 1870. The name later changed to the Duke of York Hotel.