The E.S. Levy Building, also known as the National Hotel Building is a historic structure in Galveston, Texas. Originally the Tremont Opera house, some of the walls were retained when it was re-designed as the E.S. Levy department store in 1896. It was built for E.S. Levy & Co. and Ed S. Levy. It was added to the National Register of Historic Places on November 13, 2003. The building is located at 2221-2225 Market Street.