Sir Edward Griffin (1587 – 5 May 1681) was an English politician who sat in the House of Commons from 1640 to 1644. Griffin was a son of Sir Thomas Griffin of Dingley and Gumley Ewing Northamptonshire. He matriculated at Exeter College, Oxford on 16 October 1601, aged 14. He was a student of Middle Temple in 1604. He was knighted on 20 May 1625. King James and Anne of Denmark came from Kirby Hall and visited him at Braybrooke Castle on 12 August 1605. King James knighted him at Grafton on 19 August 1608. His first wife was Lucy. He married secondly Frances Uvedale, a daughter of William Uvedale.