Sir Edward Littleton (died 1705) was an administrator of the English East India Company. He served as President of Bengal in the early eighteenth century. Littleton was the eldest son of Sir Edward Littleton, 2nd Baronet. He studied at The Queen's College, Oxford, and in 1671 married Susannah, daughter of Sir Theophilus Biddulph. From 1685 until 1689, he sat as Member of Parliament (MP) for Staffordshire.