Eitel Friedrich von Hohenzollern-Sigmaringen (25 September 1582 – 19 September 1625) was a Roman Catholic Cardinal-Priest and Prince-Bishop of Osnabrück. He was a son of Charles II, Count of Hohenzollern-Sigmaringen and thus a member of the noble and ancient Hohenzollern-Sigmaringen family. On the 15 December 1620 Pope Gregory XV created him Cardinal in pectore, he was publicly proclaimed Cardinal-Priest of on 11 Jan 1621. He was appointed Prince-Bishop of Osnabrück on 28 April 1623. On the 29 October 1623 he chose to become a priest and was ordained.