Elisha William Keyes (/kaɪs/ kies; January 23, 1828 – November 29, 1910) was an American lawyer, politician, postmaster, and local judge. He was the 6th and 22nd Mayor of Madison, Wisconsin, and represented Dane County in the Wisconsin State Assembly. He was Postmaster of Madison from the end of the Civil War until the presidency of Theodore Roosevelt. He is most known for his eight years as Chairman of the Republican Party of Wisconsin and his work building a Republican Party political machine.