Eliza Biscaccianti (1824 – July 1896) was an American operatic soprano from Boston, Massachusetts. Born Eliza Ostinelli, she was the daughter of pianist Sophia Hewitt Ostinelli, the only woman to have ever been employed as an organist and accompanist by Boston's Handel and Haydn Society and the second musician ever to perform the work of Beethoven in Boston, and , a native of Italy who became a second violinist with, and later a conductor of, the Handel and Haydn Society. Her uncle was composer John Hill Hewitt and her grandfather was conductor, composer and music publisher James Hewitt.