First Presbyterian Church of Meridian is a historic church in Meridian, Mississippi, which is listed on the National Register of Historic Places. The church was founded in 1856 by eight members including John T. Ball and Lewis A. Ragsdale, founders of the city of Meridian. The reverend at the time was William Curtis Emerson. It was listed on the National Register in 1979. It was deemed more notable than other churches in Meridian for "its historical significance" and because it was designed by P.J. Krouse, "architect of most of Meridian's outstanding buildings from 1900-1920".