The Gabriel René Moreno Autonomous University (Spanish: Universidad Autónoma Gabriel René Moreno) is a university in Santa Cruz de la Sierra, Bolivia. It was created by supreme decree of December 15, 1879. The first rector was Bishop Juan Jose Valdivia, and the first university careers offered were Medicine, Theology, and Law. The university is named after thinker, historian, and literary figure Gabriel René Moreno, called the "Prince of the Letters". The university is the fourth-best university in Bolivia, as of 2018, and is first in academic quality in the department of Santa Cruz.