Girolamo II Angelo Flavio Comneno (Latin: Hieronymus Angelus Flavius Comnenus; 1629–1687) was the Grand Master of the Constantinian Order of Saint George from 1679 to 1687. Girolamo's family, the Angelo Flavio Comneno, claimed descent from the Angelos dynasty of Byzantine emperors, and Girolamo also claimed the titles "Prince of Macedonia" and "Duke and Count of Drivasto and Durazzo".