The Greater Buckeye Conference was a high school athletic conference with six members, all located in a large area of northern and northwest Ohio. It was affiliated with the Ohio High School Athletic Association. The conference was created for the 2003-2004 school year after the Great Lakes League folded, and lasted until the end of the 2010-11 school year. The conference's longest and most storied rivalry was between the football teams of Fremont Ross and Sandusky. The Little Giants and the Blue Streaks had first played in 1895.