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Guan Yi (simplified Chinese: 管轶; traditional Chinese: 管軼; born 1962) is a Chinese virologist. In 2014, he was ranked as 11th in the world by Thomson Reuters (now known as Clarivate Analytics) among global researchers in the field of microbiology. He obtained his PhD in microbiology at the University of Hong Kong and is now a professor of microbiology at his alma mater. His research on the viral respiratory disease SARS helped the Chinese government avert the 2004 outbreak of this disease. He is the current director (China affairs) of the State Key Laboratory for Emerging Infectious Diseases University of Hong Kong. In early 2017, Guan warned that the H7N9 influenza virus "poses the greatest threat to humanity than any other in the past 100 years".

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