Henry ″Harry″ Duncan Spens Goodsir (3 November 1819 – c. 1848) was a Scottish physician and naturalist who contributed to the pioneering work on cell theory done by his brother John Goodsir. He served as surgeon and naturalist on the ill-fated Franklin expedition. His body was never found, but forensic studies in 2009 on skeletal remains earlier recovered from King William Island in Canada suggest that they may be those of Harry Goodsir.