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Hernando Pizarro y de Vargas (Spanish: [eɾˈnãndo piˈθaro]; born between 1501 and 1508, died 1578) was a Spanish conquistador and one of the Pizarro brothers who ruled over Peru. Hernando was born in Trujillo, (Extremadura), Spain, son of Captain Gonzalo Pizarro y Rodríguez de Aguilar (senior) (1446–1522) – who as colonel of infantry served in the Italian campaigns under Gonzalo Fernández de Córdoba, and in Navarre, with some distinction – and wife Isabel de Vargas.