an Entity references as follows:
A disease is holoendemic when essentially every individual in a population is infected. Although the infection is ubiquitous, symptoms of disease do not appear equally across age groups. The young are more likely to express pathogenic responses, whilst the older hosts will carry the disease asymptomatically, or with reduced damage, due to adaptive immunity. Therefore, holoendemic diseases differ from hyperendemic diseases, of which symptoms are expressed equally by members across all age groups of a population.