Holy Trinity is a Roman Catholic church located in Honolulu, Hawaiʻi. Holy Trinity Church is located in the East Honolulu neighborhood of on the island of Oʻahu, at 5919 Kalanianaole Highway (Route 72), 21°16′59″N 157°43′45″W / 21.28306°N 157.72917°W. The church serves the communities of , Kuliʻouʻou, and Hawaiʻi Kai. It falls under the jurisdiction of the Diocese of Honolulu and the bishop of Honolulu.