Holystone is a small village and former civil parish, now in the parish of Harbottle, in Northumberland, England. It lies on the edge of (and just within) the Northumberland National Park on the north bank of the River Coquet. A significant landmark is Holy Well, traditionally the site of early Christian baptisms, and the source of Holystone's water supply. In 1951 the parish had a population of 71. In the early 12th century Holystone became the home of a priory of Augustinian Canonesses. The priory buildings were demolished during the reformation in 1541.