Hopkinton City Historic District is a historic district encompassing the town center of Hopkinton, Rhode Island. The district is centered on the junction of Rhode Island Route 3 with Woodville Road, Clark Falls Road, Townhouse Road, and Old Rockville Road. It is a relatively modest town center, with twenty residences, two church buildings (one of which is no longer used as a church), the town hall, and post office. The most imposing house in the district is the Thurston-Wells House, a c. 1800 structure which was given a Victorian treatment in the mid-19th century; it stands opposite the 1836 Greek Revival First Baptist Church. The area was a major stop on the stagecoach route (now Route 3), and was eclipsed in the 20th century by the construction of Interstate 95, which passes nearby.