The Hospitaller conquest of Rhodes took place in 1306–1310. The Knights Hospitaller, led by Grand Master Foulques de Villaret, landed on the island in summer 1306 and quickly conquered most of it except for the city of Rhodes, which remained in Byzantine hands. Emperor Andronikos II Palaiologos sent reinforcements, which allowed the city to repel the initial Hospitaller attacks, and persevere until it was captured on 15 August 1310. The Hospitallers transferred their base to the island, which became the centre of their activities until it was conquered by the Ottoman Empire in 1522.