Isaac Le Maire (c. 1558 in Tournai – September 20, 1624 in Egmond aan den Hoef) was a Walloon-born entrepreneur, investor, and a sizeable shareholder of the Dutch East India Company (VOC). He is best known for his constant strife with the VOC, which ultimately led to the discovery of Cape Horn. In 1585 he settled in Amsterdam. He was married in Antwerp to Maria Jacobsdr. Walraven and they had 22 children, and one of them, his son Jacob, would go down in history as an explorer. In 1641 his son Maximiliaen became the first VOC chief of Dejima in Japan.