Isaac Odame FRCP, FRCPath, FRCPCH is a Ghanaian academic and physician who specialises in sickle cell disease. He is a professor of Hematology and Oncology at the Paediatrics department of the University of Toronto. He holds the Alexandra Yeo Chair in Hematology at the University of Toronto. He is the Director of the Hematology Division of the university's Department of Medicine. He is a staff physician of The Hospital for Sick Children, where he serves as the medical director of the Global Sickle Cell Disease Network located at the Centre for Global Child Health. He is a founder of the Global Sickle Cell Disease Network.