Jiske Griffioen (born 17 April 1985) is a Dutch professional wheelchair tennis player. In doubles, Griffioen is a 14-time major champion, Paralympic gold medalist, seven-time Masters champion, and a former world No. 1. Alongside Aniek van Koot, Griffioen completed the Grand Slam in doubles in 2013. In singles, Griffioen is a three-time Masters champion (2012, 2015, 2016), Paralympic gold medalist, four-time major champion, and a former world No. 1. Griffioen was born with spina bifida. She played wheelchair basketball representing her nation at the 2000 Sydney Olympics, aged 14.