John de Vere, 12th Earl of Oxford (23 April 1408 – 26 February 1462), was the son of Richard de Vere, 11th Earl of Oxford (1385? – 15 February 1417), and his second wife, Alice Sergeaux (1386–1452). A Lancastrian loyalist during the latter part of his life, he was convicted of high treason and executed on Tower Hill on 26 February 1462.