Karl Ludwig Nitzsch (6 August 1751 – 5 December 1831) was a German theologian, a professor of theology since 1790. Nitzsch was born in Wittenberg, where he studied from 1770 to 1775. He later served as a pastor in the towns of Beucha (from 1781) and Borna (from 1785). In 1788 he became a superintendent and consistorial assessor in Zeitz. In 1790 he obtained his doctorate in theology and during the same year became a professor at the University of Wittenberg. He was married to Louise Wernsdorf, the daughter of German rhetorician Johann Christian Wernsdorf. He died in his home city of Wittenberg.