Larry Wyche, (born 1957) is a retired United States Army Lieutenant General. He last served as the deputy commanding general of the U.S. Army Materiel Command. Prior to his last assignment, Wyche served as the Special Assistant to the Commanding General, U.S. Army Training and Doctrine Command. He has also served as commanding general of the Combined Arms Support Command, commanding general of the Sustainment Center of Excellence (SCoE) and Senior Mission Commander for Fort Lee, Virginia.