Lewis Center (also Lewis Centre) is an unincorporated community in northwestern Orange Township, Delaware County, Ohio, United States, in the Columbus, OH Metropolitan Statistical Area. Its ZIP code is 43035. Although Lewis Center is a small community, its ZIP code encompasses a number of shopping centers and retail establishments that line U.S. Route 23 in the nearby vicinity. The Lewis Center area lies on the east side of the Olentangy River, across from the city of Powell, west of Alum Creek State Park and north of the Polaris shopping hub. It is located in the Olentangy Local School District.