The Lord & Taylor Building is an 11-story commercial building in Midtown Manhattan, New York City, that formerly served as Lord & Taylor's flagship department store in the city. It is at 424–434 Fifth Avenue between 38th and 39th Streets. Designed by Starrett & van Vleck in the Italian Renaissance Revival style, the building contains a two-story base of limestone, a gray brick facade, copper cornices, and a chamfered corner. It was described as the first "frankly commercial" structure on Fifth Avenue north of 34th Street, and it replaced several of the company's previous headquarters.