Louisiana Highway 6 (LA 6) is a state highway located in western central Louisiana. It runs 54.52 miles (87.74 km) in an east–west direction from the Texas state line southwest of Many to U.S. Highway 71 (US 71) and U.S. Highway 84 (US 84) in Clarence. The route connects Many and Natchitoches, the seats of the two parishes it traverses, Sabine and Natchitoches. The bridge over the Toledo Bend Reservoir at the west end of LA 6 provides the only crossing of the state line between US 84 at Logansport, 44 miles (71 km) to the north, and LA 191 west of Leesville, 31 miles (50 km) to the south.