The Lower Brulé Indian Reservation is an Indian reservation that belongs to the Lower Brulé Lakota Tribe. It is located on the west bank of the Missouri River in Lyman and Stanley counties in central South Dakota in the United States. It is adjacent to the Crow Creek Indian Reservation on the east bank of the river. The Kul Wicasa Oyate (Khulwíčhaša Oyáte, lower…men…nation), the Lower Brulé Sioux, are members of the Sicangu (Burnt Thigh), one of the bands of the Lakota Tribe. Tribal headquarters is in Lower Brule.