"Make You Mine" is a song by Filipino singer Nina from her second studio album Smile. It was released alongside the album as its lead single in December 2003 by Warner Music Philippines. The song was written and produced by The 33rd, and features a rap verse performed by rapper Picasso. "Make You Mine" differed from the previous singles Nina was known for. Its upbeat groove and flirty lyrics allowed her to transcend the typical "love song syndrome" most Filipino artists are known for, and spun a reinvented image for the singer. The song talks about a girl who fell in love at first sight with a boy, and could not stop thinking about him and wants to make the boy hers.