Maria Full of Grace (Spanish title: María, llena eres de gracia, lit., "Maria, you are full of grace") is a 2004 drama film written and directed by Joshua Marston. The film was produced between Colombia and the United States. The story follows a Colombian girl who becomes a drug mule for a trafficking ring. Lead actress Catalina Sandino Moreno was named Best Actress at the Berlin Film Festival, and was nominated for the Academy Award for Best Actress in the 77th Academy Awards.