Mariana Duque Mariño (Spanish pronunciation: [maˈɾjana ˈðuke maˈriɲo]; born 12 August 1989) is a Colombian retired tennis player. Having turned professional in 2005, she reached a career-high singles ranking of world No. 66 in October 2015. She won her first professional tournament in May 2006, in Mazatlán, Mexico. Her biggest win in senior competition is defeating 26th seed Anna Chakvetadze in the opening round of the 2009 French Open in three sets.