Micropatterning is the art of miniaturisation of patterns. Especially used for electronics, it has recently become a standard in biomaterials engineering and for fundamental research on cellular biology by mean of soft lithography. It generally uses photolithography methods but many techniques have been developed. Nanopatterning of proteins has been achieved through using top-down lithography techniques. Aerosol micropatterning for biomaterials uses spray microscopic characteristics to obtain semi-random patterns particularly well adapted for biomaterials.