Muhammad Sultan Mirza (1375 – 1403) was a member of the Timurid dynasty and a grandson of its founder, the Central Asian conqueror Timur. As Timur's favourite grandson, Muhammad Sultan served as one of his principal military commanders, helping lead forces in successful campaigns against the Golden Horde, Persian kingdoms and the Ottoman Empire. Described by the historian Arabshah as "a manifest prodigy in his noble nature and vigour", Muhammad Sultan was eventually appointed by Timur as heir-apparent to the empire. His premature death in 1403 greatly affected his grandfather.