Murakami Yoshikiyo (村上 義清, 1501–1573) was a Japanese samurai from the and retainer of the Uesugi clan during the Sengoku period of the 16th century. Yoshikiyo followed in fighting against both Takeda Nobutora and his son Takeda Shingen. Yoshikiyo was also a very close ally under Uesugi Kenshin and one of Shingen's bitterest opponents for his high kill-counts in their conflicts. He was never able to restore his old territory and died in Echigo in 1573, and his son Murakami Kunikiyo (Yamaura Kagekuni) became retainer of Uesugi.